8:30 am Registration & Morning Coffee
Reviewing the Current Landscape of Nutritional Approaches That Modulate the Microbiome
9:00 am Diet, Microbiome and Health: Past, Present & Future
- Cindy Davis Director, Grants & Extramural Activities, NIH
• What is the evidence that diet can influence the microbiome?
• How can the microbiome influence the response to dietary components?
• What is the relationship between diet, the microbiome and disease risk?
9:30 am ADM’s Clinically Documented Probiotic Formula for Migraines
- Richard Day Head. Medical Affairs, ADM
- Exploring the role of the GI microbiome in the pathophysiology of migraine
- Examining ADM’s innovative clinical research in this field
10:00 am Rethinking Diet to Complement Gut Microbiota Function
- Patrick Veiga Director, Health & Microbiome Science, Danone Nutricia Research
• Overall diet analysis – Diet – gut microbiota analysis from clinical trial reveals functional and strain association with food categories and clinical data
• Case of consumption of multi-strain fermented milk product consumption on human gut microbiota using shotgun metagenomic – Learnings
• Towards precision nutrition: selection of strains – ingredients based on nutritional use of intestinal commensal bacteria of interest
10:30 am Speed Networking
11:30 am Outlining Ocean Spray Cranberries Interest in the Microbiome & Consumer Benefits
- Christina Khoo Director, Scientific Affairs , Ocean Spray Cranberries
• Discussing the benefits of prebiotics and synergies
• Looking at how to use the microbiome to assess the health benefits of your products
12:00 pm Mining Athlete Microbiomes for Next-Generation Probiotics
- Carolina Barsa Chief Growth & Innovation Officer , Fitbiomics
12:30 pm Building a Comprehensive Platform to Accelerate the Development of Microbiome-based Therapeutics
- Martha Carlin CEO & Co-founder , The BioCollective
- Collecting high quality samples for more robust data analysis
- Connecting the dots with a world class strain bank and in- depth microbial
- Creating an end-to end testing and development platform to accelerate
12:40 pm Lunch & Networking
Harnessing Nutrition to Improve GI Health & the Immune System
1:30 pm Oral Microbial Therapy for the Management of Pediatric Respiratory Allergies
- Azza Gadir Director, R&D, Seed Health
• Primary prevention of allergic disease has proved an elusive goal despite the dramatic increase in prevalence over the past decade
• There is increasing evidence that the airway and gut microbiome influences the development of airway and food allergies
• Probiotics are increasingly considered as a promising early life intervention to prevent the development of allergies and decrease severity of reactions
2:00 pm The Role of the Gut Microbiome on Human Gastrointestinal & Immune Health
- Lucien Harthoorn Director, R&D , Clasado Biosciences
• The importance of the gut microbiome in human health and disease; what have we learned from human studies so far
• Evidence-base and benefits of pre- and probiotics in gastrointestinal and immune health; what is after the bifidogenic effect?
• New approaches in microbiome modulation building on the pre- & probiotics evidence base; what is already there and what is still needed to fill the gaps?
2:30 pm Gut Microbiota-targeted Dietary Fiber Intervention to Improve Intestinal Inflammation: Opportunities and Challenges
- Vishal Singh Assistant Professor, Nutritional Physiology & Microbiome , The Pennsylvania State University
• Therapeutic potential of targeting gut microbiome and metabolome in inflammatory bowel disease (IBD)
• Dietary fiber(s)-based nutritional interventions to induce a beneficial
and predictable shift in gut microbiota composition: the promise and reality
• Why do patients with IBD report poor tolerance to certain dietary fibers?
3:00 pm Afternoon Break & Networking
3:30 pm Diet-Microbiome Study Design Mastermind
- Abigail Johnson Research Scientist , University of Minnesota
Although an increasing number of microbiome studies collect some form of dietary data or perform diet interventions, there are no clear standards in the microbiome field for how to collect diet data or how to design a
diet-microbiome study. This session will present a variety of considerations including both practical recommendations that can be immediately incorporated into studies and aspirational recommendations that will require greater effort for implementation. Questions to be discussed include:
• How do you do a diligent study when there are so many variables you cannot control with free-living people?
• How do you weigh competing interests of time, cost, and quality when designing a microbiome study?
• Strategies to ensure compliance in your test population?
• Can studies be designed to improve detection of dietary interventions?
Effectively Targeting the Microbiome in Early Life for Optimized Health Outcomes
4:30 pm Insights Into the Reason & Potential Role of Bifidobacterium Being the Natural Inhabitant of the Infant Gut
- Xiao Jin-Zhong General Manager, Next Generation Science Institute, Morinaga Milk Industry
• Understanding how Bifidobacterium naturally occurs in and adapts to the human gut and its possible mother-to-infant vertical transmission routes
• Outlining the distinguished metabolic profile of infant-type Human- Residential Bifidobacteria (HRB) that contribute to their preponderance in the infant gut and their health benefits to the infant host
• Highlighting the key clinical effects of Human-Residential Bifidobacteria (HRB) supplementation on infant health, particularly the vulnerable preterm infants
5:00 pm Baby-SHIME® Technology Platform: A Step by Step Approach for PreClinical Product Testing on the Infant Gut Microbiome
- Aurelien Baudot Head, Business Development , ProDigest
• Introducing Baby-SHIME®: an in vitro simulation of the infant gastrointestinal tract
• Revealing efficient pre-clinical testing in a funnel approach: delivery, efficacy, long-term modulation
• Demonstrating the impact of HMOs on gut microbiota activity and composition
5:15 pm Examining Nutrition as the Key Determinant of Age-Appropriate Microbiota Development in Infants and Children
- Olga Sakwinska Senior Scientist , Nestle Research
• Understanding optimal microbiota development link to diverse health outcomes
• Discussing breastmilk as the gold standard for infant nutrition
• Looking beyond breastfeeding: complementary diets for maturing microbiota
5:55 pm Refreshment Break
6:15 pm Evening Workshop Discussions – Ingredient Deep Dive
Advancing the Future of Prebiotics
Emerging research has suggested that the composition and abundance of the beneficial microbes in the gut can be impacted through the addition of non-digestible prebiotic compounds. There is also now a movement towards understanding how more specific compounds such as polyphenols can positively impact the microbiota. The session will seek to define what a prebiotic is, explore
how they can be utilized to improve health and discuss future frameworks for product development. Discussion points include:
- Learn about the emerging prebiotic ingredients
- Learn about the state and gaps in science
- Learn about aligning emerging science and consumer comprehension
Len Monheit, Executive Director /CEO, Global Prebiotic Association /Trust Transparency Center
Advancing the Future of Probiotics
Development of probiotic supplements that claim to promote health are being commonplace across the globe. Even with the science of probiotics being thoroughly researched there has been a number of papers that suggest that many of the commercially available strains may not elicit the positive outcomes they claim to. This session will highlight key advances in the field, tackle the limitations of probiotics and highlight future avenues of opportunity for the development of dietary supplements.
Advancing the Future of Postbiotics
With the rise of microbiome sampling technologies, increasing evidence has shown metabolites including SCFA and bacteriocins derived from the beneficial bacteria in the gut are responsible for the positive health outcomes observed. These postbiotics and how they can be harnessed to improve health are gathering research interest, so this session will explore their subsequent applications in the nutritional community.
Aubrey Levitt, CEO, Postbiotics Plus