8:35 am Coffee & Networking
9:10 am Chair’s Opening Remarks
Driving Precision for Development of Effective & Personalized Nutritional Products
9:20 am Accelerating Personalization of Probiotics for Greater Optimal Health Outcomes
Synopsis
- Gut diversity and impact within chronic conditions
- IBS and stratifying solutions based on microflora composition and genetic potential
- ASD and paving the way for gut-brain axis models
9:50 am Session Details to Be Announced
Synopsis
10:00 am Growth Failure & the Microbiome in Preterm Infants
Synopsis
- Description of the normal microbiome of preterm infants and how it is altered
- Early data on how the microbiome differs in poorly growing preterm infants versus those with normal growth
- Discussion of the future directions for our groups’ investigations
10:30 am Changing the Trajectory of Infant Health Through Ground breaking Discoveries
11:00 am Morning Break & Refreshments
Leveraging the Power of the Gut-Brain Axis to Develop Clinically Validated Products
11:30 am Optimizing Study Design of Probiotic & Other Microbiome Products – Avoiding Pitfalls for Study Success
Synopsis
- Discussion of various study designs
- Importance of understanding your endpoints of interest
- Staying away from diseased states or conditions
12:00 pm Causal Effect Relationship Between Stress Induced Depression in Alzheimer’s Disease (AD) Progression Through Single Bacteria Modulating Regulatory T Cell (Treg) & Th17 Cells (Th17) Immunity
Synopsis
- The synbiotic is more consistent than the probiotic or prebiotic at promoting behavioral resilience to stress-induced psychological impairment
- The synbiotic (and probiotic) may modify the gut microbiota populations to elicit the ileal-specific immune regulation
- Treg/Th17 ratio in the periphery directs associates with the recruitment of peripheral immune cells to the limbic brain regions, including the hippocampus and prefrontal cortex
12:30 pm Investigating the Use of Probiotics to Support Antidepressant Treatment
Synopsis
- Review of the gut-brain axis and the reciprocal links between the gut microbiome and neurological physiology
- Dysbiosis and depression – Do patients with clinical depression have different microbiomes?
- Probiotics and Depression – Can altering the microbiome with probiotics have an impact on neurological outcomes? Review of the current published data
- Clinical trial review – Visbiome High Potency Probiotic recent randomized controlled trial as an add-on modality for the clinically depressed
1:00 pm Lunch & Networking
Understanding the Impact of Diet on Gut Health to Overcome Disease
2:00 pm The Edible Plant Microbiome & Human Health
Synopsis
- Edible plants deliver microbes contributing to health
- The extent of diversity is vast, representing an attractive source for new products
- How Solarea developed a platform to harness these novel probiotics
2:30 pm Nutrition 2.0: Highly Personalized, Data-Driven & Focused on Chronic Health
Synopsis
- Viome Life Sciences has built an open access, systems biology platform for human health applications
- We have developed a direct-to-consumer personalized nutrition application with integrated clinical research for continuous improvement
- We will show preliminary efficacy data from our interventional trial
3:00 pm Exploring the Relationship Between Diet Diversity, Microbiota Composition & Disease to Optimize Healthy Outcomes
Synopsis
- Investigating diet approaches to reduce the levels of starting bacterial species associated with diseases
- Utilizing diet and probiotics to modulate microbiome composition to reduce the abundance of species that are detrimental to health
- Discussing the potential of AI/machine learning algorithms to predict individual microbiome responses to changes in dietary patterns and nutrients