CONFERENCE DAY TWO
WEDNESDAY, NOVEMBER 13

7.30

Registration & Morning Coffee

 

 

Microbiome Insights For Personalised Nutrition

Session Purpose:

More knowledge of the your individual gut microbiome composition leads to the generation of person-specific information that can be utilized to assist in personalized diagnostic assessment and targeted treatment options. A number of breakthrough organizations are beginning to take patient-specific microbial data and develop new individualised approaches that enable us to truly access the power of the human microbiome. The purpose of this theme will be to review the current efforts used to collect, interpret and analyse microbiome-specific data to create personalized nutrition solutions of the future.

8.30

Building a Platform for Personalized Diet Recommendations That Are Based on Gut Microbiome Chemistry and Math Algorithms

• Metatranscriptomics enables microbial gene expression analysis
• Microbial pathways allow understanding of food substrates and microbial
metabolites
• Understanding the microbiome chemistry and using AI models allows us to
make personalized diet recommendations

Momo Vuyisich
CSO
Viome

9.00

Machine Learning in the Microbiome: Providing Predictable Personalized Nutrition based on Your Gut

• Developing and commercializing an algorithm the predicts blood sugar responses based on the gut microbiome
• Sharing new clinical research
• Creating new insights to address and treat metabolic disorders

Lihi Segal
CEO
DayTwo

9.30

A Personalized Dietary Framework for Exploiting the Fermentation Capabilities of a Patient’s Microbiota

• Addressing how the same dietary fibre impacts the composition of the microbiota differently in different people
• Different people produce different metabolites from the same dietary fibre input
• Exploiting these differences between patients to devise personalized nutrition strategies and improve clinical outcomes

Thomas Gurry
Senior Research Associate
University of Geneva

10.30

Morning Coffee & Refreshments Break

Infant & Paediatric Microbiome

Session Purpose:

Gut microbiome development is a lengthy, complex and vital process which starts in utero and continues after birth. During the early stages of growth, the gut microbiome composition that is finally established may influence the development of disease later on in life. As such, the infant microbiome has been targeted as an exciting area for researchers and organizations with a nutrition focus. The purpose of this theme is to provide a better understanding into the current research and commercial efforts that are ongoing that aim to understand the factors of supporting the infant gut microbial composition during critical periods (prenatal, perinatal and postnatal) and use that insight into breakthrough nutritional and supplement products of the future.

11.00

A Multi’omic Dive into Understanding How Diet Modulates Host-Microbiome Interactions in Human Infants

• Understanding in human milk regulate intestinal development and microbiome composition
• Identifying clinically-relevant host, microbiome and metabolite biomarkers that differentiate breastfed and formula-fed infants
• Applying this information to improve infant formula composition

Sharon Donovan
Professor
University of Illinois

11.30

Human Milk Directs the Function of Bifidobacteria within the Infant Gut Microbiome

• Individual human milk oligosaccharides are differentially metabolized by bifidobacteria in a strain-dependent manner
• Differential bifidobacterial metabolism impacts microbiome community structure and function
• This could have profound implications in developing infant nutrition and health interventions

David Sela
Assistant Professor
University of Massachusetts Amherst

12.00

The Natural Symbiosis between B. infantis and HMO Provides Colonization Resistance for the Early Infant Gut – A Clinical Update

• The pH of the infant gut microbiome has increased dramatically over the past 100 yr resulting in a loss of colonization resistance.
• The loss of colonization resistance results in chronic gut inflammation within 40 days of birth
• Colonization resistance can be re-established in the breastfed infant by supplying B. infantis, a key commensal that is missing in 9 out of every 10 babies born in the US today

David Kyle
Executive Chairman and CSO
Evolve Biosystems

12.30

Understanding the Role of Human Milk Oligosaccharides in Infant Nutrition

• Infant intestinal microbiome development and dynamics
• Importance of HMOs in shaping early microbiota maturation and immune system development
• Showcasing recent data from an observational study and an intervention trial

Bernard Berger
Senior Scientist
Nestle Research 

13.00

Baby-SHIME Technology Platform: A Step by Step Approach for
Pre-Clinical Product Testing on the Infant Gut Microbiome

Aurelien Baudot
International Business Developer
ProDigest

13.15

Lunch & Networking

Regulatory and Intellectual Property Guidance -
Challenges for Microbiome-Based Claims in Health & Wellness

Session Purpose:

As the current regulatory guidance distinguishing between drug and food based claims through the microbiome remain confusing, there is a need to create clearer guidelines that incentivize innovation into breakthrough nutritional interventions for disease risk management and overall health and wellness. The purpose of this theme will be to create an open dialogue between basic and clinical scientists, regulatory authorities and industry to review the current regulatory guidance for nutritional products based on targeting of the microbiome whilst highlighting the critical challenges that need to be overcome.

14.00

An Overview of the Patent and Regulatory Landscape for Microbiomebased Interventions in Nutrition

• To understand innovation and patent activity in the area of human microbiome within nutrition
• Competitive intelligence: Key organizations and technology adoption trends
• Reviewing clinical trials and regulatory developments related to microbiomebased interventions in nutrition

Anil Sharma
Researcher
University of Minnesota

14.30

Reviewing Regulatory Frameworks and Claims for Beverages That Leverage Novel Microbiome Insights

Christina Khoo
Director, Global Health Science & Nutrition Policy
Ocean Spray Cranberries

15.00

Aligning Regulatory Frameworks, Consumer Insights and R&D for Successful Probiotic Claims and Communications

• Successful claims and communication should have a fine balance between consumer and scientific insights
• Science should be simple enough for consumer
• Prebiotic and postbiotic applications are interesting trends

Nalin Siriwardhana
Program Manager Nutritional Sciences
Church & Dwight

Investment, Partnerships & Policy to Accelerate Microbiome Innovation in Nutrition

Session Purpose:

Despite global advancements in microbiome science and technology. the majority of innovators in the microbiome field are small or early stage companies, eager to obtain financing to fuel further development. Despite the challenges associated with translating microbiome science into successful dietary interventions, many strategic and private investors have begun to take major stakes in microbiome-focused businesses. This theme will review the current investment landscape for microbiome-focused science in the food, nutrition and nutraceutical industry and share key components for success stories.

15.30

Partnering with Mondelez to Disrupt the Functional Food Category Through Products That Focus on Gut Health

• Partnering as a tool to strengthen global capacity of your product
• How to navigate a new space in the nutritional market
• Maintaining core values

Kara Landau
CEO and Head Dietician
Uplift Food

Future Trends in Food Science & The Microbiome

Session Purpose:

The microbiome has proven efficacy across a range of health indications, many of which have already been explored at this
year’s discussion. The purpose of this concluding theme will be to review some of the most exciting areas and trends the human microbiome will impact as it relates to food science and nutrition.

16.00

Dietary Plant-Derived Microbial Mediators and Intestinal Homeostasis

• Exosome-like nanoparticles (ELNs) mediate interkingdom communication
• Plant diets impact the gut microbiome and intestinal homeostasis
• Plant-derived ELNs are potential microbiome-mediating bioactives

Jennifer Spinler
Instructor
Texas Children’s Microbiome Center & Baylor College of Medicine

16.30

Close of 3rd Microbiome Movement – Human Nutrition Summit